4-Nitrophenethyl bromide → HCID 21278908, compound

Participants

Reaction Steps

1-(4-Nitrophenyl)piperazine (4.14 g), 4-nitrophenethyl bromide (4.6 g) and sodium bicarbonate (3.4 g) in acetonitrile (75 ml) were stirred under reflux for 1 day, and then evaporated to dryness. The residue was then triturated with water (300 ml), filtered, washed with water (300 ml), and the resulting solid was crystallized from ethyl acetate, yielding the title compound, (3.62 g), m.p. 143°-5°.

Provenance & Evidence