HCID 21278908, compound → HCID 21278914, compound

Participants

Reaction Steps

1-(4-Nitrophenyl)-4-(4-nitrophenethyl)piperazine (3.35 g) in methylated spirit (400 ml) was hydrogenated at 45° and 60 psi over 10% Pd/C (about 300 mg) for 3 hours. The catalyst was then removed by filtration and the filtrate evaporated to dryness, giving an off-white residual solid which was crystallized from ethyl acetate (charcoal); yield of the title compound 2.1 g, m.p. 156°-8°.

Provenance & Evidence