反应详情

4-Methanesulphonamidophenethyl methanesulphonate (1.47 g) and 1-(4-methanesulphonamido-3-methylphenyl)piperazine 1/4 hydrate (1.37 g) in ethanol (15 ml) were refluxed overnight, evaporated to dryness, and partitioned between ethyl acetate and water. The title compound (0.2 g) was filtered from the 2-phase mixture and recrystallised from methanol/acetone, yield 0.128 g, m.p. 235°-7°.

1. customevaporated to dryness
2. custompartitioned between ethyl acetate and water
3. filtrationThe title compound (0.2 g) was filtered from the 2-phase mixture
4. customrecrystallised from methanol/acetone, yield 0.128 g, m.p. 235°-7°