HCID 13393783, compound → Flavanone

HRID 2291614Notes

Reaction equation

HRID 2291614 reaction equation
[C:1]1([CH:7]2[C:12]3C=C(C([O-])=O)S[C:11]=3[C:10]3[CH:19]=[CH:20][CH:21]=[CH:22][C:9]=3[O:8]2)[CH:6]=[CH:5][CH2:4][CH2:3][CH:2]=1.[Na+].ClC1C2C(=CC=CC=2)[O:28]C(C2C=CC=CC=2)C=1C=O>CO>[O:8]1[C:9]2[C:10](=[CH:19][CH:20]=[CH:21][CH:22]=2)[C:11](=[O:28])[CH2:12][CH:7]1[C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 13393783HCID 13393783, compoundHCID 86742664HCID 86742664, compound

Product 1

HCID 10251Flavanone

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Analogously, (-)-sodium 4H-4-phenyl-thieno[3,2-c][1]benzopyran-2-carboxylate, [α]43625 =-89° (c=0.5, methanol), is prepared starting from the pure enantiomeric 4-chloro-3-formyl-flav-3-ene which is obtained by chloroformylation of (-)-flavanone [(-) at 436 nm]. The preparation of (+)- and (-)-flavanone is described e.g. in Tetrahedron Lett. 26, 2305 (1970) and Acta Chim. Acad. Sci. Hung. 86, 161 (1975).

Sources & evidence

ORD record
ord-bdbaefea736741dba3da8d06e92fc148
Source dataset
uspto-grants-1989_01
Patent number
US04797414

Reaction notes

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