反应详情

Propionitrile (13.2 g, 0.24 mole), ethyl pentafluoropropionate (23.05 g, 0.12 mole) and a solution of n-butyllithium in n-hexane (168 ml, 0.264 mole) were reacted as the procedure illustrated in the preceding Preparation 1 to give 22.72 g (crude yield 94.1%) of the crude title compound. The yield calculated as the pure product was 84.1%. The resulting compound was dissolved in CDCl3 to measure NMR, the ratio of the keto form/the enol form was found to be 71/29, b.p. 63°-65° C./28 mmHg.

1. customillustrated in the preceding Preparation 1