Thionyl Chloride → 4,4-Dimethylcyclohexane-1-carbonyl chloride

HRID 2291724Notes

Reaction equation

HRID 2291724 reaction equation
[CH3:1][C:2]1([CH3:11])[CH2:7][CH2:6][CH:5]([C:8](O)=[O:9])[CH2:4][CH2:3]1.S(Cl)([Cl:14])=O>>[CH3:1][C:2]1([CH3:11])[CH2:7][CH2:6][CH:5]([C:8]([Cl:14])=[O:9])[CH2:4][CH2:3]1

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 139287434,4-Dimethylcyclohexanecarboxylic acid

Product 1

HCID 212793424,4-Dimethylcyclohexane-1-carbonyl chloride

Procedure

To 5 g of 4,4-dimethyl-cyclohexylcarboxylic acid was added an excess of thionyl chloride, and the mixture was heated with stirring for 3 hours. After the reaction, the remaining thionyl chloride was distilled off in a vacuum, 10 ml of benzene was added to the residue and the mixture was distilled in a vacuum, giving oily 4,4-dimethylcyclohexylcarbonyl chloride.

Workup

  1. temperaturethe mixture was heated
  2. customAfter the reaction
  3. distillationthe remaining thionyl chloride was distilled off in a vacuum, 10 ml of benzene
  4. additionwas added to the residue
  5. distillationthe mixture was distilled in a vacuum

Sources & evidence

ORD record
ord-00f1aeaab6f8426b9f1604bc34d1a888
Source dataset
uspto-grants-1989_01
Patent number
US04797502

Reaction notes

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