DL-Tyrosine → HCID 131715817, compound

Participants

Reaction Steps

The Boc-precursor of the titled compound is prepared according to the method of Example 2 using the diastereomer, N[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-tyrosyl-N-(3-phenylpropyl)-D-alaniamide, in place of its DL-tyrosine containing analogs. The resulting 2,6-dimethyl-O-[(phenylamino)carbonyl]-L-tyrosyl-N-(3-phenylpropyl)-D-alaninamide is then reacted with glacial acetic acid and 6.8N HCl-dioxane according to the method of Example 3 to produce the titled hydrochloride.

Provenance & Evidence