HCID 14373528, compound → HCID 131715819, compound

HRID 2291751Notes

Reaction equation

HRID 2291751 reaction equation
CC(C)(OC([NH:7][C@H:8]([C:28]([NH:30][C@@H:31]([C:33]([NH:35][CH2:36][CH2:37][CH2:38][C:39]1[CH:44]=[CH:43][CH:42]=[CH:41][CH:40]=1)=[O:34])[CH3:32])=[O:29])[CH2:9][C:10]1[C:15]([CH3:16])=[CH:14][C:13]([O:17][C:18]([O:20][C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)=[O:19])=[CH:12][C:11]=1[CH3:27])=O)C.[ClH:46].O1CCOCC1>C(O)(=O)C>[ClH:46].[CH3:16][C:15]1[CH:14]=[C:13]([O:17][C:18]([O:20][C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)=[O:19])[CH:12]=[C:11]([CH3:27])[C:10]=1[CH2:9][C@@H:8]([C:28]([NH:30][C@@H:31]([C:33]([NH:35][CH2:36][CH2:37][CH2:38][C:39]1[CH:44]=[CH:43][CH:42]=[CH:41][CH:40]=1)=[O:34])[CH3:32])=[O:29])[NH2:7]

Participants

4

Reactant 2

HCID 14373528HCID 14373528, compoundHCID 204431481,4-Dioxane hydrochloride

Product 1

HCID 131715819HCID 131715819, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

The product of Example 13 is dissolved in glacial acetic acid and reacted with 6.8N HCl-dioxane according to the method of Example 3 to produce the titled hydrochloride compound.

Sources & evidence

ORD record
ord-481feda5d8d04e71a681210522624d36
Source dataset
uspto-grants-1989_01
Patent number
US04797470

Reaction notes

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