Sodium Chloride → HCID 13605019, compound

Participants

Reaction Steps

At 20° C., 242 mg of potassium borohydride were introduced into a solution of 400 mg of the product of Step A, 30 ml of tetrahydrofuran and 4 ml of water and the mixture was stirred for 15 minutes at ambient temperature. 10 ml of a saturated aqueous solution of sodium chloride were added with stirring for 5 minutes at 20° C. and after extracting with ethyl acetate, drying and concentrating, 410 mg of 3-nitro-1-(2-propynyl)-1H-pyrrole-4-methanol were obtained melting at 60° C.

Provenance & Evidence