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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2291948Generated: October 26, 2026

Isoquinoline-5-sulfonyl chloride hydrochloride → 1-(5-Isoquinolinesulfonyl)-3-hydroxy-5-methylpyrrolidine

https://huagongshe.com/reaction/2291948

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsoquinoline-5-sulfonyl chloride hydrochlorideHCID 13116932—
Reactant5-Methylpyrrolidin-3-olHCID 21973779—
Product1-(5-Isoquinolinesulfonyl)-3-hydroxy-5-methylpyrrolidineHCID 21278320—

Reaction Steps

In substantially the same manner as in Example 11, 2.64 g of 5-isoquinolinesulfonyl chloride hydrochloride was reacted with 2.0 g of 3-hydroxy-5-methylpyrrolidine to obtain 1-(5-isoquinolinesulfonyl)-3-hydroxy-5-methylpyrrolidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04798897
Source datasetuspto-grants-1989_01
ORD IDord-03e8df5658404f978996ea1be23a6610
Source noteuspto-grants-1989_01