Thionyl Chloride → HCID 21277820, compound

HRID 2291996Notes

Reaction equation

HRID 2291996 reaction equation
S(Cl)([Cl:3])=O.[Cl:5][C:6]1[CH:7]=[C:8]([Cl:24])[C:9]2[O:13][C:12]([CH:14]([C:16]3[CH:21]=[CH:20][C:19]([Cl:22])=[CH:18][CH:17]=3)O)=[CH:11][C:10]=2[CH:23]=1>C1CCCCC1>[Cl:5][C:6]1[CH:7]=[C:8]([Cl:24])[C:9]2[O:13][C:12]([CH:14]([Cl:3])[C:16]3[CH:21]=[CH:20][C:19]([Cl:22])=[CH:18][CH:17]=3)=[CH:11][C:10]=2[CH:23]=1

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 3068791(4-Chlorophenyl)(5,7-dichloro-1-benzofuran-2-yl)methanol

Product 1

HCID 21277820HCID 21277820, compound

Reagents, catalysts & solvents 1

HCID 8078CyclohexaneSolvent

Procedure

To 0.35 mole of thionylchloride in 300 ml of cyclohexane, 0.31 mole of (5,7-dichlorobenzofuran-2-yl)(p-chlorophenyl)carbinol are portions-like added followed by 3-hour agitation at ambient temperature; then the solution is concentrated, filtered out and crystallized from cyclohexane: m.p. 72°-74° C.

Workup

  1. additionadded
  2. waitfollowed by 3-hour
  3. customat ambient temperature
  4. concentrationthen the solution is concentrated
  5. filtrationfiltered out and
  6. customcrystallized from cyclohexane

Sources & evidence

ORD record
ord-fc871e6b687946cb9ad72340a16f66bf
Source dataset
uspto-grants-1989_01
Patent number
US04800208

Reaction notes

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