HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenacyl bromide → HCID 14349724, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenacyl bromide | HCID 6259 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 14349717 | HCID 14349717 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 14349724 | HCID 14349724 | 101.9% |
Reaction Steps
A mixture of 539 mg of (6R-trans)-3-[(acetyloxy)methyl]-7-[(aminothioxomethyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, diphenylmethyl ester, 240 mg of 2-bromo-1-phenylethanone, 85 mg of potassium carbonate and 7 ml of acetonitrile was stirred overnight, then filtered through hydrous magnesium silicate. The filtrate was evaporated, giving 660 mg of the desired compound [α]D26 =+68°±3° (c, 0.4 chloroform).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04800199 |
| Source dataset | uspto-grants-1989_01 |
| ORD ID | ord-e4c0ff49e9184048b1aa72c24feb2405 |
| Source note | uspto-grants-1989_01 |