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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2292053Generated: October 31, 2026

Trifluoroacetic acid → HCID 14349736, compound

https://huagongshe.com/reaction/2292053

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantAnisoleHCID 7519—
ReactantHCID 14349734HCID 14349734—
SolventDichloromethaneHCID 6344—
ProductHCID 14349736HCID 1434973673.2%

Reaction Steps

A mixture of 300 mg of (6R-trans)-3-[(acetyloxy)methyl]-7-[(4-carboxy-2-thiazolyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, diphenylmethyl ester, 1 ml of trifluoroacetic acid, 0.25 ml of anisole and 3 ml of dichloromethane was allowed to stand for 45 minutes, then the solid was collected, washed with ether and petroleum ether and dried, giving 155 mg of the desired compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04800199
Source datasetuspto-grants-1989_01
ORD IDord-44c46e2bc1614d0b8adc0b2ec69c990d
Source noteuspto-grants-1989_01