HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl Ether → HCID 14349740, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Anisole | HCID 7519 | — |
| Reactant | HCID 14349738 | HCID 14349738 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 14349740 | HCID 14349740 | 80.4% |
Reaction Steps
A mixture of 175 mg of (6R-trans)-3-[(acetyloxy)methyl]-8-oxo-7-[[4-[[(phenylmethyl)amino]carbonyl]-2-thiazolyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, diphenylmethyl ester, trifluoroacetic acid and anisole in dichloromethane was stirred for 45 minutes. The addition of dichloromethane, ether and petroleum ether caused precipitation. The solid was collected and washed with ether and petroleum ether, giving 105 mg of the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04800199 |
| Source dataset | uspto-grants-1989_01 |
| ORD ID | ord-2fe1fa6771ed4a0690e8f1c05bc7e37f |
| Source note | uspto-grants-1989_01 |