Ammonium Chloride → HCID 14307646, compound

Participants

Reaction Steps

To a solution of 2-(4-methoxybenzyl)-3-methyl-5-propyl-4,7-benzofurandione (from Preparation 28) (295 mg, 0.91 mmol) in MeOH (3 mL) were added NH4Cl (109 mg) and NaN3 (130 mg). The mixture was heated to reflux for 4 hours and the solvent was then removed in vacuo. Water was added and the product was extracted into CH2Cl2 and chromatographed on silica gel (15% EtOAc/hexane) to give the title compound.

Provenance & Evidence