HCID 14330456, compound → 5-Methoxy-3,4-dihydro-2H-1-benzothiopyran-3-amine

Participants

Reaction Steps

A solution of 10 g of N-t-butoxycarbonyl-3,4-di-hydro-5-methoxy-2H-[1]-benzothiopyran-3-amine in 30 mL of trifluoroacetic acid is kept at room temperature for 1 hr. The solvent is removed in vacuo, the residue is treated with 1N NaOH and the product is extracted with ether. After drying over magnesium sulfate, the solvent is removed in vacuo to afford 3,4-dihydro-5-methoxy-2H-[1]-benzothiopyran-3-amine as an oil.

Provenance & Evidence