HRID2292187

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：O=C(c1cc(O)c(O)c(O)c1)c1ccc(O)c(O)c1O

HCID40399

Exifone

C13H10O7

HCID62493

2,2-Dimethylpropanoyl chloride

C5H9ClO

PRODUCTS

生成物

结构：CC(C)(C)C(=O)Oc1cc(C(=O)c2ccc(OC(=O)C(C)(C)C)c(OC(=O)C(C)(C)C)c2OC(=O)C(C)(C)C)cc(OC(=O)C(C)(C)C)c1OC(=O)C(C)(C)C

HCID14010408

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID1049

Pyridine

C5H5N

PROCEDURE

实验过程

100 mg of 3,4,5,4',5',6'-hexahydroxy benzophenone (0.00036 mole) and 450 MG (0.004 mole) of pivaloyl chloride were warmed to 50° C. in 20 mls of pyridine for 4 hrs. Solvent removed via N2 stream. Water added and extraction of product was done via CH2Cl2. The organic layer was washed with K2CO3 (5%) and dried over MgSo4. Solvent removal left an oil. 250 mg. (88%) yield.

WORKUP

后处理

customSolvent removed via N2 stream
additionWater added
extractionextraction of product
washThe organic layer was washed with K2CO3 (5%)
customdried over MgSo4
customSolvent removal
waitleft an oil
custom(88%) yield

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-8d2c2458b1184cd184c7b5162797bcff
来源数据集: uspto-grants-1989_01
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04801610
来源说明: uspto-grants-1989_01

反应 SMILES

[OH:1][C:2]1[CH:3]=[C:4]([CH:16]=[C:17]([OH:20])[C:18]=1[OH:19])[C:5]([C:7]1[C:12]([OH:13])=[C:11]([OH:14])[C:10]([OH:15])=[CH:9][CH:8]=1)=[O:6].[C:21](Cl)(=[O:26])[C:22]([CH3:25])([CH3:24])[CH3:23]>N1C=CC=CC=1>[C:21]([O:1][C:2]1[CH:3]=[C:4]([CH:16]=[C:17]([O:20][C:21](=[O:26])[C:22]([CH3:25])([CH3:24])[CH3:23])[C:18]=1[O:19][C:21](=[O:26])[C:22]([CH3:25])([CH3:24])[CH3:23])[C:5]([C:7]1[C:12]([O:13][C:21](=[O:26])[C:22]([CH3:25])([CH3:24])[CH3:23])=[C:11]([O:14][C:21](=[O:26])[C:22]([CH3:25])([CH3:24])[CH3:23])[C:10]([O:15][C:21](=[O:26])[C:22]([CH3:25])([CH3:24])[CH3:23])=[CH:9][CH:8]=1)=[O:6])(=[O:26])[C:22]([CH3:25])([CH3:24])[CH3:23]