4-Hydroxybenzophenone → {4-[(But-2-en-1-yl)oxy]phenyl}(phenyl)methanone

Participants

Reaction Steps

4-crotyloxybenzophenone was prepared from 4-hydroxybenzophenone and crotyl bromide using the procedure of Example 23. Through Claisen rearrangement it was converted into 3-(α-methyl-allyl)-4-hydroxybenzophenone. The crude product (10.1 g) was acylated (procedure of Example 1) and purified by chromatography (40:60 hexane-methylene chloride on silica gel) to produce 12.25 g (91%) of oil.

Provenance & Evidence