HCID 131715841, compound → HCID 131715840, compound

HRID 2292350Notes

Reaction equation

HRID 2292350 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([CH:9]([NH:36][C:37]([O:39]C(C)(C)C)=[O:38])[C:10]([NH:12][NH:13][S:14]([NH:17][C:18]([N:20]2[CH2:23][C@H:22]([NH:24][C:25](=[O:34])[O:26][CH2:27][C:28]3[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=3)[C:21]2=[O:35])=[O:19])(=[O:16])=[O:15])=[O:11])[CH:5]=[CH:6][C:7]=1[OH:8]>CCOCC>[OH:1][C:2]1[CH:3]=[C:4]([CH:9]([NH:36][C:37]([O:39][CH2:9][C:4]2[CH:5]=[CH:6][CH:7]=[CH:2][CH:3]=2)=[O:38])[C:10]([NH:12][NH:13][S:14]([NH:17][C:18]([N:20]2[CH2:23][C@H:22]([NH:24][C:25](=[O:34])[O:26][CH2:27][C:28]3[CH:29]=[CH:30][CH:31]=[CH:32][CH:33]=3)[C:21]2=[O:35])=[O:19])(=[O:15])=[O:16])=[O:11])[CH:5]=[CH:6][C:7]=1[OH:8]

Participants

3

Reactant 1

HCID 131715841HCID 131715841, compound

Product 1

HCID 131715840HCID 131715840, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

Freeze drying of the aqueous phase yielded, after stirring with ether, an additional 2.5 g of (S)-[1-[[[[2-[(3,4-dihydroxyphenyl)[[(t-butyloxy)carbonyl]amino]acetyl]hydrazino]sulfonyl]amino]carbonyl]-2-oxo-3-azetidinyl]carbamic acid, phenylmethyl ester.

Workup

  1. customFreeze drying of the aqueous phase
  2. customyielded

Sources & evidence

ORD record
ord-3bb3eb7ce5f74b37b4ea02dad07f832b
Source dataset
uspto-grants-1989_01
Patent number
US04801705

Reaction notes

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