N-methyl-N-(trimethylsilyl)trifluoroacetamide → HCID 57187641, compound

HRID 2292359Notes

Reaction equation

HRID 2292359 reaction equation
CN([Si:9]([CH3:12])([CH3:11])[CH3:10])C(=O)C(F)(F)F.[CH3:13][N:14]([C:16](=[O:25])[C:17]1[CH:22]=[CH:21][C:20](O)=[C:19](O)[CH:18]=1)[NH2:15]>>[CH3:13][N:14]([C:16](=[O:25])[C:17]1[CH:22]=[CH:21][C:20]([Si:9]([CH3:12])([CH3:11])[CH3:10])=[C:19]([Si:9]([CH3:12])([CH3:11])[CH3:10])[CH:18]=1)[NH2:15]

Participants

3

Reactant 2

HCID 32510N-methyl-N-(trimethylsilyl)trifluoroacetamideHCID 57280465HCID 57280465, compound

Product 1

HCID 57187641HCID 57187641, compound

Conditions

Temperature
50 °C

Procedure

9.53 ml of N-methyl-N-(trimethylsilyl)trifluoroacetamide (0.051 mol) was added to a suspension of 4.2 g of 3,4-dihydroxybenzoic acid, 1-methylhydrazide (0.023 mol). After warming the suspension to 50° C. for one hour, a clear solution of 3,4-bis(trimethylsilyl)benzoic acid, 1-methylhydrazide was obtained.

Sources & evidence

ORD record
ord-55814b2899b9441fbfce952c35797234
Source dataset
uspto-grants-1989_01
Patent number
US04801705

Reaction notes

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