Trifluoroacetic acid → HCID 131715847, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 20 ml of thioanisole and 75 ml of trifluoroacetic acid was cooled to 0° C. and 15.25 g of (S)-[1-[[[[[[3-(3,4-dihydroxyphenyl)-2-oxo-1-imidazolidinyl]carbonyl]amino]sulfonyl]amino]carbonyl]-2-oxo-3-azetidinyl]carbamic acid, phenylmethyl ester, monosodium salt was added. After stirring overnight at room temperature, the excess trifluoroacetic acid was evaporated in vacuo and the residue triturated with ether. The precipitate was filtered off by suction, washed with ether, and dried in vacuo; yield: 15.69 g.

Provenance & Evidence