Trifluoroacetic acid → HCID 131715851, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 16 ml of trifluoroacetic acid and 4 ml of thioanisole was cooled to 0° C., and 4 g (7.7 mmol) of (S)-[1-[[[[3-(3,4-dihydroxyphenyl)-2-oxo-1-imidazolidinyl]sulfonyl]amino]carbonyl]-2-oxo-3-azetidinyl]carbamic acid, phenylmethyl ester was added. The mixture was stirred overnight at room temperature, evaporated in vacuo, and the residue triturated with ether. The precipitate was filtered off by suction, washed with ether, dichlormethane and isopropanol and dried in vacuo; yield: 3.19 g.

Provenance & Evidence