[2,3-bis(Acetyloxy)benzoyl]hydrazinecarboxylic acid, t-butyl ester → HCID 86742714, compound

HRID 2292378Notes

Reaction equation

HRID 2292378 reaction equation
C([O:4][C:5]1[C:21]([O:22]C(=O)C)=[CH:20][CH:19]=[CH:18][C:6]=1[C:7]([N:9]([C:11]([O:13][C:14]([CH3:17])([CH3:16])[CH3:15])=[O:12])[NH2:10])=[O:8])(=O)C>CO.N>[OH:4][C:5]1[C:21]([OH:22])=[CH:20][CH:19]=[CH:18][C:6]=1[C:7]([N:9]([C:11]([O:13][C:14]([CH3:17])([CH3:16])[CH3:15])=[O:12])[NH2:10])=[O:8]

Participants

4

Reactant 1

HCID 86742713[2,3-bis(Acetyloxy)benzoyl]hydrazinecarboxylic acid, t-butyl ester

Product 1

HCID 86742714HCID 86742714, compound

Reagents, catalysts & solvents 2

HCID 222AmmoniaSolventHCID 887MethanolSolvent

Procedure

[2,3-bis(Acetyloxy)benzoyl]hydrazinecarboxylic acid, t-butyl ester (25 g) was dissolved in 100 ml of methanol containing 6 g of ammonia. After standing over 24 hours at 0° C., the solvent was removed in vacuo and the residue stirred with 100 ml of ice water yielding (2,3-dihydroxybenzoyl)hydrazinecarboxylic acid, t-butyl ester as beige crystals, 17.8 g; melting point 158°-160° C.

Workup

  1. customthe solvent was removed in vacuo

Sources & evidence

ORD record
ord-8812e9835bbe4e0e8272d4e6a9ca2d9f
Source dataset
uspto-grants-1989_01
Patent number
US04801705

Reaction notes

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