1-Bromo-4-iodobenzene → HCID 21477971, compound

Participants

Reaction Steps

Quantities: tetrakis(triphenylphosphine)palladium(0) (0.87 g, 0.75 mmol), compound from Example 47 (9 g, 30 mmol) and 1-bromo-4-iodobenzene (7.07 g, 25 mmol). The experimental procedure was as described in Example 48 except that the reaction was carried out under conditions of reflux (5 h). The crude product was purified by flash column chromatography (light petrol/dichloro methane, 5:1) to give a colourless solid (9 g) which was recrystallised from light petrol to yield colourless crystals.

Provenance & Evidence