HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2,3-Difluorophenyl)boronic acid → 2-(2,3-Difluorobiphenyl-4'-yl)-5-octyl-1,3-dioxane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2,3-Difluorophenyl)boronic acid | HCID 2734333 | — |
| Reactant | 2-(4'-Bromophenyl)-5-n-octyl-1,3-dioxane | HCID 12924967 | — |
| Catalyst | HCID 178418397 | HCID 178418397 | — |
| Solvent | Sodium Carbonate | HCID 10340 | — |
| Product | 2-(2,3-Difluorobiphenyl-4'-yl)-5-octyl-1,3-dioxane | HCID 21477975 | — |
Reaction Steps
Quantities: compound from Example 14 (10.7 g, 30 mmol), compound from Example 36 (5.5 g, 35 mmol), tetrakis(triphenylphosphine)palladium(0) (1.04 mg, 0.9 mmol) and aqueous sodium carbonate (30 cm3, 2M). The experimental procedure was as described in Example 63.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05683623 |
| Source dataset | uspto-grants-1997_11 |
| ORD ID | ord-9ac42e18da964919bfa8e3fc5ce013b9 |
| Source note | uspto-grants-1997_11 |