HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus tribromide → 1-(Bromomethyl)-2,5-dichloro-3-methoxybenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus tribromide | HCID 24614 | — |
| Reactant | 2,5-Dichloro-3-methoxybenzyl alcohol | HCID 21478119 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 1-(Bromomethyl)-2,5-dichloro-3-methoxybenzene | HCID 21478105 | 86.6% |
Reaction Steps
By the method of Example 1, Step B, 13.95 grams (0.0674 mole) of 2,5-dichloro-3-methoxyphenylmethanol and 7.295 grams (0.270 mole) of phosphorus tribromide were reacted in toluene, yielding 15.76 grams of 2,5-dichloro-3-methoxyphenylmethyl bromide as an oil. The NMR spectrum was consistent with the proposed structure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05683966 |
| Source dataset | uspto-grants-1997_11 |
| ORD ID | ord-9ac6bf8e458f4e39b36adc1c7a19b250 |
| Source note | uspto-grants-1997_11 |