HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2292593Generated: November 1, 2026
Azobisisobutyronitrile → tert-Butyl 2-(4-(bromomethyl)phenyl)-2-cyclopentylacetate
https://huagongshe.com/reaction/2292593
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Azobisisobutyronitrile | HCID 6547 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | Tert-butyl 2-cyclopentyl-2-(4-methylphenyl)acetate | HCID 15234721 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | tert-Butyl 2-(4-(bromomethyl)phenyl)-2-cyclopentylacetate | HCID 15225592 | — |
Reaction Steps
27.4 g (0.1 mol) of the compound from Example XXI are dissolved in 200 ml of tetrachloromethane and the solution is heated to boiling. After addition of 0.82 g of azobisisobutyronitrile, 18.7 g (0.105 mol) of N-bromosuccinimide are added in portions and the mixture is then refluxed for 1 h, cooled to 0° C. and succinimide is filtered off. After concentrating the filtrate the product precipitates. It is washed with petroleum ether (40/60) and dried.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05684014 |
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| Source dataset | uspto-grants-1997_11 |
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| ORD ID | ord-ea51c5b247f14ee391a700f158130688 |
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| Source note | uspto-grants-1997_11 |
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