1,2,3,4-Tetrahydro-1-naphthaleneacetic acid → HCID 18918721, compound

HRID 2292640Notes

Reaction equation

HRID 2292640 reaction equation
[CH:1]1([CH2:11][C:12](O)=O)[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][CH2:2]1.[CH3:15][O:16][C:17]1[C:18]([N:26]2[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]2)=[CH:19][C:20]2[O:24][CH2:23][CH2:22][C:21]=2[CH:25]=1>>[CH3:15][O:16][C:17]1[C:18]([N:26]2[CH2:27][CH2:28][N:29]([CH2:12][CH2:11][CH:1]3[C:10]4[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=4)[CH2:4][CH2:3][CH2:2]3)[CH2:30][CH2:31]2)=[CH:19][C:20]2[O:24][CH2:23][CH2:22][C:21]=2[CH:25]=1

Participants

3

Reactant 2

HCID 128585751,2,3,4-Tetrahydro-1-naphthaleneacetic acidHCID 15839404HCID 15839404, compound

Product 1

HCID 18918721HCID 18918721, compound

Procedure

Prepared as described in Example 9, starting from 1,2,3,4-tetrahydronaphthalen-1-ylacetic acid and 4-(2,3-dihydro-5-methoxybenzofuran-6-yl)piperazine. The fumarate of the title compound melts at 219°-220° C. after recrystallisation from ethanol.

Workup

  1. customPrepared
  2. customThe fumarate of the title compound melts at 219°-220° C. after recrystallisation from ethanol

Sources & evidence

ORD record
ord-70bbcc5d16624599be4b02c9f40a04c1
Source dataset
uspto-grants-1997_11
Patent number
US05684020

Reaction notes

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