Fumarate → HCID 18918752, compound

HRID 2292642Notes

Reaction equation

HRID 2292642 reaction equation
[S:1]1[CH2:5][CH:4]=[C:3]2[CH:6]=[C:7]([C:9](O)=O)[CH:8]=[C:2]12.[CH3:12][O:13][C:14]1[C:15]([N:23]2[CH2:28][CH2:27][NH:26][CH2:25][CH2:24]2)=[CH:16][C:17]2[O:21][CH2:20][CH2:19][C:18]=2[CH:22]=1.C([O-])(=O)/C=C/C([O-])=O>>[S:1]1[CH2:5][CH:4]=[C:3]2[CH:6]=[C:7]([CH2:9][N:26]3[CH2:27][CH2:28][N:23]([C:15]4[C:14]([O:13][CH3:12])=[CH:22][C:18]5[CH2:19][CH2:20][O:21][C:17]=5[CH:16]=4)[CH2:24][CH2:25]3)[CH:8]=[C:2]12

Participants

4

Reactant 3

HCID 5460307FumarateHCID 15839404HCID 15839404, compoundHCID 18918729HCID 18918729, compound

Product 1

HCID 18918752HCID 18918752, compound

Procedure

Prepared as described in Example 9, starting from (cyclopenta[b]thien-5-yl)carboxylic acid (Preparation 8) and 4-(2,3-dihydro-5-methoxybenzofuran-6-yl)piperazine. The fumarate of the title compound melts at 186°-190° C. (ethanol).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-9f073b781cd3409a93452c46d5fff23e
Source dataset
uspto-grants-1997_11
Patent number
US05684020

Reaction notes

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