1,2-dihydroacenaphthylene-1-carboxylic acid → HCID 18918735, compound

HRID 2292644Notes

Reaction equation

HRID 2292644 reaction equation
[CH:1]1([C:13](O)=O)[C:11]2=[C:12]3[C:7](=[CH:8][CH:9]=[CH:10]2)[CH:6]=[CH:5][CH:4]=[C:3]3[CH2:2]1.[CH3:16][O:17][C:18]1[C:19]([N:27]2[CH2:32][CH2:31][NH:30][CH2:29][CH2:28]2)=[CH:20][C:21]2[O:25][CH2:24][CH2:23][C:22]=2[CH:26]=1.C([O-])(=O)/C=C/C([O-])=O>>[CH:1]1([CH2:13][N:30]2[CH2:29][CH2:28][N:27]([C:19]3[C:18]([O:17][CH3:16])=[CH:26][C:22]4[CH2:23][CH2:24][O:25][C:21]=4[CH:20]=3)[CH2:32][CH2:31]2)[C:11]2=[C:12]3[C:7](=[CH:8][CH:9]=[CH:10]2)[CH:6]=[CH:5][CH:4]=[C:3]3[CH2:2]1

Participants

4

Reactant 3

HCID 40711081,2-dihydroacenaphthylene-1-carboxylic acidHCID 5460307FumarateHCID 15839404HCID 15839404, compound

Product 1

HCID 18918735HCID 18918735, compound

Procedure

Prepared as described in Example 9, starting from acenaphthen-1-ylcarboxylic acid and 4-(2,3-dihydro-5-methoxybenzofuran-6-yl)piperazine. The fumarate of the title compound melts at 226°-228° C. (ethanol).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-f0ae1c9269644adf9d3bc3652ddfc535
Source dataset
uspto-grants-1997_11
Patent number
US05684020

Reaction notes

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