Fumarate → HCID 18918748, compound

HRID 2292645Notes

Reaction equation

HRID 2292645 reaction equation
[CH3:1][O:2][C:3]1[C:4]([N:13]2[CH2:18][CH2:17][NH:16][CH2:15][CH2:14]2)=[CH:5][C:6]2[O:11][CH2:10][CH2:9][O:8][C:7]=2[CH:12]=1.[C:19]([O-])(=O)/[CH:20]=[CH:21]/[C:22]([O-])=O>>[CH3:1][O:2][C:3]1[C:4]([N:13]2[CH2:14][CH2:15][N:16]([CH2:19][CH:20]3[CH2:6][C:7]4[C:22](=[CH:5][CH:4]=[CH:3][CH:12]=4)[CH2:21]3)[CH2:17][CH2:18]2)=[CH:5][C:6]2[O:11][CH2:10][CH2:9][O:8][C:7]=2[CH:12]=1

Participants

3

Reactant 2

HCID 5460307FumarateHCID 18918724HCID 18918724, compound

Product 1

HCID 18918748HCID 18918748, compound

Procedure

Prepared as described in Example 9, starting from 4-(2,3-dihydro-7-methoxybenzo-1,4-dioxin-6-yl)piperazine (Preparation 5). The fumarate of the title compound melts at 176°-178° C. (ethanol).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-0812d81ad61e47cf94df5defae4a33a0
Source dataset
uspto-grants-1997_11
Patent number
US05684020

Reaction notes

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