Pyridine → 4'-[[2-n-Butyl-6-(N-methyl-phenylaminocarbonylamino)-benzimidazol-1-yl]-methyl]biphenyl-2-carboxylic acid

Participants

Reaction Steps

A solution of 0.8 g (2.00 mMol) of 4'-[[2-n-butyl-6-aminobenzimidazol-1-yl]-methyl]biphenyl-2-carboxylic acid and 0.9 g of N-methyl-isatoic acid anhydride in 3 ml of pyridine is refluxed for 48 hours, then evaporated to dryness, the residue is suspended in about 5 ml of methylene chloride, suction filtered, washed with a further 5 ml of methylene chloride and dried.

Provenance & Evidence