Sodium Hydroxide → HCID 178479084, compound

Participants

Reaction Conditions

Reaction Steps

A 5-L, 3-neck, round bottom flask equipped with a mechanical stirrer and a thermometer was charged with (4) (150 g, 0.47 mol) and water (5 L). The pH of the suspension was adjusted to 6.5 by adding 5M aqueous sodium hydroxide dropwise, and the resulting suspension was cooled to 5° C. for 2 hours. The off-white solid was collected by filtration, washed with water (2 L) and t-butyl methyl ether (1 L), and dried for 24 hours at 60° C. and 20 mm Hg to provide 115 g (87%) of (5).

Provenance & Evidence