HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl propiolate → Ethyl 1-methyl-1H-pyrrole-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl propiolate | HCID 12182 | — |
| Reactant | N-formylsarcosine | HCID 11789184 | — |
| Solvent | Acetic Anhydride | HCID 7918 | — |
| Product | Ethyl 1-methyl-1H-pyrrole-3-carboxylate | HCID 11062584 | 88.4% |
Reaction Steps
The same procedure as in Example 1 was carried out using 15.64 g (0.134 mole) of N-formylsarcosine, 49.00 g (0.499 mole) of ethyl propiolate, and 107 ml of acetic anhydride to obtain 18.08 g (yield 88.4%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05684161 |
| Source dataset | uspto-grants-1997_11 |
| ORD ID | ord-681c8c469fd74b47886fb0a86b7c4363 |
| Source note | uspto-grants-1997_11 |