HCID 21480176, compound → HCID 21480173, compound

HRID 2292883Notes

Reaction equation

HRID 2292883 reaction equation
[C:1](C1C=C(C(=O)CSCC)C=C(C(C)(C)C)C=1O)(C)(C)C.[C:22]([C:26]1[CH:27]=[C:28]([C:37](=[O:43])[CH2:38][S:39]([CH3:42])(=[O:41])=[O:40])[CH:29]=[C:30]([C:33]([CH3:36])([CH3:35])[CH3:34])[C:31]=1[OH:32])([CH3:25])([CH3:24])[CH3:23]>>[C:22]([C:26]1[CH:27]=[C:28]([C:37](=[O:43])[CH2:38][S:39]([CH2:42][CH3:1])(=[O:41])=[O:40])[CH:29]=[C:30]([C:33]([CH3:36])([CH3:35])[CH3:34])[C:31]=1[OH:32])([CH3:23])([CH3:24])[CH3:25]

Participants

3

Reactant 2

HCID 21480176HCID 21480176, compoundHCID 21480177HCID 21480177, compound

Product 1

HCID 21480173HCID 21480173, compound

Procedure

This material is prepared from impure 1-(3,5-di-t-butyl-4-hydroxyphenyl)-2-(ethylsulfanyl)ethanone (following the method of 1-(3,5,-di-t-butyl-4-hydroxyphenyl)-2-(methylsulfonyl)ethanone). Crystallization (of the crude product) from EtOAc/hexanes followed by a second crystallization then a flash chromatography with EtOAc followed by a third crystallization with refrigeration gives white crystals, mp=119.5°-120.5° C.

Workup

  1. customCrystallization (of the crude product) from EtOAc/hexanes
  2. customfollowed by a second crystallization
  3. customa flash chromatography with EtOAc followed by a third crystallization with refrigeration
  4. customgives white crystals, mp=119.5°-120.5° C.

Sources & evidence

ORD record
ord-eb14a18252844460a28eda52eb465576
Source dataset
uspto-grants-1997_11
Patent number
US05684204

Reaction notes

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