Succinic anhydride → HCID 21479636, compound

HRID 2292974Notes

Reaction equation

HRID 2292974 reaction equation
[Br:1][C:2]1[S:3][CH:4]=[CH:5][CH:6]=1.[C:7]1(=O)[O:12][C:10](=O)[CH2:9][CH2:8]1.[Cl-].[Al+3].[Cl-].[Cl-].[NH2:18][NH2:19]>C(O)C>[Br:1][C:2]1[S:3][C:4]([N:18]2[C:10](=[O:12])[CH2:9][CH2:8][CH:7]=[N:19]2)=[CH:5][CH:6]=1

Participants

6

Reactant 4

HCID 7922Succinic anhydrideHCID 9321HydrazineHCID 138512-BromothiopheneHCID 6451240Aluminum(III) Chloride

Product 1

HCID 21479636HCID 21479636, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

(5-Bromo-2-thienyl)-1,4,5,6-tetrahydropyridazin-6-one was prepared as in Example 41 condensing 2-bromothiophene and succinic anhydride with aluminum chloride followed by reaction with hydrazine in ethanol.

Sources & evidence

ORD record
ord-e9af27b446d84b6d8491c3c0377b11b2
Source dataset
uspto-grants-1997_11
Patent number
US05684151

Reaction notes

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