Potassium Hydroxide → HCID 21475745, compound

HRID 2293029Notes

Reaction equation

HRID 2293029 reaction equation
I.[NH:2]=[C:3]1[N:7]([CH2:8][CH2:9][CH2:10][CH3:11])[CH2:6][CH2:5][S:4]1.[OH-].[K+]>CO>[NH:2]=[C:3]1[N:7]([CH2:8][CH2:9][CH2:10][CH3:11])[CH2:6][CH2:5][S:4]1

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 21475767HCID 21475767, compound

Product 1

HCID 21475745HCID 21475745, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Then, the 2-imino-3-n-butylthiazolidine hydroiodide was stirred together with 5.28 g (80 mmol) of 85% potassium hydroxide in 300 ml of methanol at room temperature for one hour. Methanol was distilled off under reduced pressure. Then, 200 ml of chloroform was added to the residue, and precipitated insoluble matters were removed by filtration. Chloroform was distilled off under reduced pressure, and 6.9 g of 2-imino-3-n-butylthiazolidine was obtained by distillation under reduced pressure.

Workup

  1. distillationMethanol was distilled off under reduced pressure
  2. additionThen, 200 ml of chloroform was added to the residue
  3. customprecipitated insoluble matters
  4. customwere removed by filtration
  5. distillationChloroform was distilled off under reduced pressure

Sources & evidence

ORD record
ord-69da62dc7ec642c3887c05e528142e2e
Source dataset
uspto-grants-1997_11
Patent number
US05686390

Reaction notes

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