Methanol → HCID 54238938, compound

HRID 2293036Notes

Reaction equation

HRID 2293036 reaction equation
I.[CH3:2][N:3]1[CH2:7][C:6](=[O:8])[N:5]([CH2:9][CH2:10][CH3:11])[C:4]1=[NH:12].CO.[OH-].[K+]>>[CH3:2][N:3]1[CH2:7][C:6](=[O:8])[N:5]([CH2:9][CH2:10][CH3:11])[C:4]1=[NH:12]

Participants

4

Reactant 3

HCID 887MethanolHCID 14797Potassium HydroxideHCID 676185061-Methyl-3-n-propyl-2-iminoimidazolidin-4-one hydroiodide

Product 1

HCID 54238938HCID 54238938, compoundYield 74.7%

Procedure

2.83 g (10 mmol) of the 1-methyl-3-n-propyl-2-iminoimidazolidin-4-one hydroiodide was added to 25 ml of methanol containing 0.66 g (10 mmol) of 85% potassium hydroxide, and the mixture was stirred at room temperature for one hour. Methanol was distilled off under reduced pressure, and chloroform was added to the residue. Precipitated crystals were removed by filtration. Chloroform was distilled off under reduced pressure to obtain 1.16 g of 1-methyl-3-n-propyl-2-iminoimidazolidin-4-one as an oily substance.

Workup

  1. distillationMethanol was distilled off under reduced pressure, and chloroform
  2. additionwas added to the residue
  3. customPrecipitated crystals
  4. customwere removed by filtration
  5. distillationChloroform was distilled off under reduced pressure

Sources & evidence

ORD record
ord-223b29e7c8a34940934cb553c4a61ccb
Source dataset
uspto-grants-1997_11
Patent number
US05686390

Reaction notes

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