HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 15307986, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2-(Trifluoromethoxy)benzoyl Chloride | HCID 2777241 | — |
| Reactant | 5-(4-Aminobenzoyl)-6,11-dihydro-5H-dibenz[b,e]azepine | HCID 15410467 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 15307986 | HCID 15307986 | 69.7% |
Reaction Steps
As described for Example 9, 0.314 g (1.0 mmol) of 5-(4-aminobenzoyl)-6,11-dihydro-5H-dibenz[b,e]azepine is reacted with 0.247 g (1.1 mmol) of 2-(trifluoromethoxy)benzoyl chloride and 0.111 g (1.1 mmol) of triethylamine in 10 ml of dichloromethane at room temperature for 1.5 hours. The product is triturated with dichloromethane-hexane to give 0.35 g of crystals, m.p. 232°-235° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05686445 |
| Source dataset | uspto-grants-1997_11 |
| ORD ID | ord-8b641989a5b94c18a47faf180c0d1cbd |
| Source note | uspto-grants-1997_11 |