HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 15307987, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2-(Methylsulfanyl)benzoyl chloride | HCID 12576798 | — |
| Reactant | 5-(4-Aminobenzoyl)-6,11-dihydro-5H-dibenz[b,e]azepine | HCID 15410467 | — |
| Reactant | Ethyl acetate hexane | HCID 21226206 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 15307987 | HCID 15307987 | 32.3% |
Reaction Steps
As described for Example 9, a mixture of 0.242 g of 2-(methylthio)benzoyl chloride (m.p. 61°-64° C.), 0.134 g of triethylamine and 0.314 g of 5-(4-aminobenzoyl)-6,11-dihydro-5H-dibenz[b,e]azepine in 10 ml of dichloromethane is stirred for 2.5 hours and worked up to give a solid. Trituration with ethyl acetate-hexane gives 0.150 g of crystals, m.p. 222°-225° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05686445 |
| Source dataset | uspto-grants-1997_11 |
| ORD ID | ord-51a06011027745b68fb281622e72b883 |
| Source note | uspto-grants-1997_11 |