Benzyl mercaptan → 4-(benzylthio)benzonitrile

Participants

Reaction Steps

A mixture of 37.2 g (300 mmol) of benzylmercaptan, 36.3 g (300 mmol) of 4-fluorobenzonitrile and 42 g of potassium carbonate in 700 ml of 2-butanone is refluxed for 7 hours. The solvent is evaporated off under vacuum and the residue is taken up with water and petroleum ether. The crystals formed are filtered off and washed with water and then with petroleum ether to give 46 g of 4-(benzylthio)benzonitrile in the form of crystals melting at 85° C.

Provenance & Evidence