Cesium carbonate → HCID 67620037, compound

Participants

Reaction Steps

Using the procedure described in example 5, treatment of L-proline-L-isoleucine benzylamide (296 mg, 0.93 mmol), with cesium carbonate (0.61 g, 1.87 mmol), and 2-bromo-2'-acetonaphthone (697 mg, 2.80 mmol, 3.0 eq) in acetonitrile (12 mL), provided 364 mg (80%) of L-isoleucine, N-[1-(2-naphth-2-yl-2-oxoethyl)-L-prolyl] benzylamide as a pale yellow oil.

Provenance & Evidence