Bromomethyl 4-methoxyphenyl ketone → HCID 67621352, compound

Participants

Reaction Steps

Using the procedure described in example 5, treatment of L-proline-L-isoleucine benzylamide (208 mg, 0.65 mmol), with sodium carbonate (104 mg, 0.98 mmol), and 2-bromo-4'- methoxyacetophenone (195 mg, 0.85 mmol, 1.3 eq) in MeOH (10 mL), provided 248 mg (81%) of L-isoleucine, N-[1-(2-(4-methoxyphenyl)-2-oxoethyl)-L-prolyl] benzylamide as a pale yellow oil.

Provenance & Evidence