Sodium Carbonate → HCID 67619690, compound

Participants

Reaction Steps

Using the procedure described in example 5, treatment of L-proline-L-isoleucine benzylamide (196 mg, 0.62 mmol), with sodium carbonate (85 mg, 0.80 mmol), and 2-bromopropiophenone (210 mg, 0.98 mmol, 1.6 eq) in MeOH (12 mL), provided 72 mg (26%) of L-isoleucine, N-[1-(1-methyl-2-phenyl-2-oxoethyl)-L-prolyl] benzylamide.

Provenance & Evidence