Triethylamine → HCID 67620867, compound

Participants

Reaction Steps

Using the procedure described in Example 5, treatment of a solution of L-proline-L-isoleucine benzylamide (54 mg, 0.17 mmol), with triethylamine (118 uL, 0.84 mmol, 5.0 eq), and 2-bromo-2'-nitroacetophenone (50 mg, 0.20 mmol, 1.2 eq) in THF (5 mL), provided 46 mg (57%) of L-isoleucine, N-[1-(2-(2-nitrophenyl)-2-oxoethyl)-L-prolyl] benzylamide.

Provenance & Evidence