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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 229337Generated: October 26, 2026

Thiomorpholine → N-(5-methyl-1H-pyrazol-3-yl)-2-styryl-6-thiomorpholinopyrimidin-4-amine

https://huagongshe.com/reaction/229337

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThiomorpholineHCID 67164—
Reactant3-Phenylprop-2-enenitrileHCID 74667—
Reactant1H-Pyrazol-3-amine, 5-methyl-HCID 93146—
ProductN-(5-methyl-1H-pyrazol-3-yl)-2-styryl-6-thiomorpholinopyrimidin-4-amineHCID 66738864—

Reaction Steps

Example 83 was synthesized via Scheme 6 according to the general scheme provided above with the appropriate starting materials cinnamonitrile, 5-methyl-1H-pyrazole-3-amine, and thiomorpholine. Structure of the target was confirmed by 1H-NMR. The 1H-NMR is attached.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07563787B2
Source datasetuspto-grants-2009_07
ORD IDord-8d020d0e0d044e83a58c04eb0072de0f
Source noteuspto-grants-2009_07