4-Fluoroaniline → HCID 86613125, compound

HRID 229338Notes

Reaction equation

HRID 229338 reaction equation
[C:1](#[N:10])[CH:2]=[CH:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[CH3:11][C:12]1[NH:16][N:15]=[C:14]([NH2:17])[CH:13]=1.[F:18][C:19]1[CH:25]=[CH:24][C:22]([NH2:23])=[CH:21][CH:20]=1>>[F:18][C:19]1[CH:25]=[CH:24][C:22]([NH:23][C:3]2[CH:2]=[C:1]([NH:17][C:14]3[CH:13]=[C:12]([CH3:11])[NH:16][N:15]=3)[N:10]=[C:1]([CH:2]=[CH:3][C:4]3[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=3)[N:10]=2)=[CH:21][CH:20]=1

Participants

4

Reactant 3

HCID 97314-FluoroanilineHCID 746673-Phenylprop-2-enenitrileHCID 931461H-Pyrazol-3-amine, 5-methyl-

Product 1

HCID 86613125HCID 86613125, compound

Procedure

Example 86 was synthesized via Scheme 6 according to the general scheme provided above with the appropriate starting materials cinnamonitrile, 5-methyl-1H-pyrazole-3-amine, and 4-fluoroaniline. Structure of the target was confirmed by 1H-NMR. The 1H-NMR is attached.

Workup

  1. customExample 86 was synthesized via Scheme 6 according to the general scheme
  2. customprovided above with the

Sources & evidence

ORD record
ord-767ad7fed8954bbfbbe8ce1caa3602f7
Source dataset
uspto-grants-2009_07
Patent number
US07563787B2

Reaction notes

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