3-Phenoxybenzoic acid → HCID 131720298, compound

Participants

Reaction Steps

Using the procedure described in Example 5, treatment of L-proline-L-isoleucine benzylamide (200 mg, 0.63 mmol) with 3'-phenoxy-2-chloroacetophenone (233 mg, 0.95 mmol, 1.5 eq; prepared from 3-phenoxybenzoic acid by the method described in Example 1) provided 80 mg of L-isoleucine, N-[1-(2-(3-phenoxyphenyl)-2-oxoethyl)-L-prolyl] benzylamide as a foam.

Provenance & Evidence