2-Phenoxybenzoic acid → HCID 131720299, compound

Participants

Reaction Steps

Using the procedure described in Example 5, treatment of L-proline-L-isoleucine benzylamide (200 mg, 0.63 mmol) with 2'-phenoxy-2-chloroacetophenone (233 mg, 0.95 mmol, 1.5 eq; prepared from 2-phenoxybenzoic acid by the method described in Example 1) provided 40 mg of L-isoleucine, N-[1-(2-(2-phenoxyphenyl)-2-oxoethyl)-L-prolyl] benzylamide as a foam.

Provenance & Evidence