(3S,5S,6R,10R)‐6‐Hydroxy‐10‐propyl‐4,9‐dioxatricyclo[5.4.0.03,5]undec‐1(7)‐ene‐2,8‐dione → HCID 11831537, compound

Participants

Reaction Steps

EI-1941-3 is prepared from EI-1941-2 stored at room temperature in the dry state. EI-1941-2 (80 mg) which had been stored was dissolved in 4 ml of methanol. The solution was divided into two portions (2 ml each) and each portion was passed through HPLC column (D-ODS-5-B S-5 120A, YMC). Elution was carried out with 30% acetonitrile at a flow rate of 20 ml/min to separate EI-1941-2-containing fractions and EI-1941-3-containing fractions. The EI-1941-3-containing fractions were combined and concentrated to dryness under reduced pressure to give 13 mg of EI-1941-3.

Provenance & Evidence